Aldol condensation
Carbonyl enolate addition followed by dehydration to form alpha,beta-unsaturated carbonyl compounds.
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Organic Reaction Guides
Fast reference pages for highly searched organic reactions. Each guide includes a concise scheme, two common examples, reaction SMILES, key conditions, and an edit-in-MolDraw button.
Wittig reaction
Conversion of aldehydes or ketones to alkenes using phosphonium ylides.
Open guideGrignard reaction
Carbon-carbon bond formation using organomagnesium reagents and carbonyl electrophiles.
Open guideSuzuki coupling
Palladium-catalyzed coupling of aryl halides and boronic acids to form biaryls.
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Palladium-catalyzed arylation or vinylation of alkenes.
Open guideFriedel-Crafts acylation
Electrophilic aromatic substitution that installs an acyl group on an aromatic ring.
Open guideDiels-Alder reaction
Concerted cycloaddition between a conjugated diene and dienophile to form cyclohexenes.
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