Organic reaction

Wittig Reaction

The Wittig reaction converts aldehydes or ketones into alkenes using a phosphonium ylide. It is one of the most searched named reactions for alkene synthesis.

Reaction Scheme

aldehyde or ketone + phosphonium ylide -> alkeneOften run in ether, THF, or hydrocarbon solvents depending on ylide stability.

Primary reaction SMILES: O=Cc1ccccc1.C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>C=Cc1ccccc1

Two Common Examples

Benzaldehyde to styrene

Benzaldehyde plus methylene ylide gives styrene.

Cyclohexanone olefination

Cyclohexanone can be converted to methylenecyclohexane.

MolDraw Use

Open the reaction in MolDraw to edit reactant labels, add conditions, or export a clean scheme.