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PharmaFree
SAR table template
Free template. Download it, or open it in MolDraw to change it first.
A 4-anilinoquinazoline core with two attachment points (R¹, R²) and an editable structure–activity table: R-groups, illustrative example IC₅₀ values and RDKit-computed cLogP, with blank rows ready to fill in.
What the template shows
- A scaffold with R¹/R² handles and a table to record analogues — replace the example data with your own
- Core scaffold (4-anilinoquinazoline)
- Analogue table (example data — edit freely)
- # R¹ R² IC₅₀ (nM)* cLogP (calc.) 1 H H 850 3.37 2 H OMe 320 3.38 3 Cl OMe 45 4.04 4 Br OMe 38 4.14 5 F OMe 120 3.52 6 OMe H 1100 3.38 7 8
- * IC₅₀ values are illustrative example data, not measured. cLogP is the RDKit Crippen value for the full analogue. Add rows and columns (potency, selectivity, solubility, notes) as you go.
- A structure–activity relationship (SAR) table holds one series on a common scaffold: each row is an analogue, each column a property.
- Vary one handle at a time (R¹, then R²) so a change in activity can be traced to one change in structure.
- Keep a computed lipophilicity column (cLogP or cLogD) beside potency to watch ligand efficiency and avoid “molecular obesity”.
- The example IC₅₀ values here are placeholders for a 4-anilinoquinazoline-style series; swap in your own numbers.
- The table is a real, editable table: double-click a cell to edit, and add rows or columns.
- Illustrative template; example data only · every part of this sheet is editable
Drawn with 17 atoms, 5 shapes – every one editable in MolDraw.
Sources
How to use this template
- Press Edit in MolDraw. The template opens on the canvas of the free MolDraw editor.
- Change anything: move structures, edit atoms and labels, recolour highlights or delete what you do not need.
- Add your own structures, arrows and text next to it, or combine several templates on one page.
- Export the drawing as PNG, SVG or PDF for slides, worksheets, theses and papers.
Frequently asked questions
Is the SAR table template free?
Yes. The SAR table template is one of the free MolDraw templates: open it in the editor or download it from this page as SVG or PNG and use it in your slides, worksheets and notes.
Can I edit the SAR table template?
Yes. It opens as an ordinary MolDraw drawing, so every structure, arrow, label and colour can be changed, and you can add your own content around it.
Is the chemistry checked?
Every structure is checked with RDKit and every curly arrow passes MolDraw’s electron-flow audit. The sources used are listed on this page.
Are the IC₅₀ values in the SAR table real?
No. They are illustrative example values so the table can be filled in with your own data; the structures and R-group positions are checked with RDKit.