LogP Calculator

Enter a SMILES string or compound name to retrieve PubChem XLogP, a hydrophobicity estimate used in medicinal chemistry and formulation screening.

Enter a compound to calculate.
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What LogP Tells You

LogP estimates the partitioning of a neutral compound between octanol and water. Higher LogP generally means a compound is more hydrophobic; very high values can indicate lower aqueous solubility and possible permeability/formulation tradeoffs.