Druglikeness Calculator

Enter a SMILES string or compound name to calculate a simple druglikeness guideline score from Lipinski and Veber-style properties.

How the Druglikeness Score Works

This tool combines six common medicinal chemistry property checks: Lipinski molecular weight, LogP, H-bond donors, H-bond acceptors, plus Veber-style TPSA and rotatable bond checks. The score is the percentage of these checks that pass.

• Use it for quick triage, teaching, and early compound comparison.
• Do not treat the score as a prediction of potency, safety, or approval likelihood.
• Natural products, macrocycles, prodrugs, and specialized target classes may fall outside these simple guidelines.