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Michael addition template
Free template. Download it, or open it in MolDraw to change it first.
The acetone enolate adds to methyl vinyl ketone at the β-carbon; the enolate formed is protonated.
Mechanism step by step
Conjugate (1,4-) addition of an enolate to an enone
- Conjugate addition – The enolate attacks the β-carbon
- Protonation – Water protonates the new enolate
Key points
- Soft, stabilised nucleophiles add 1,4; hard ones (RLi) add 1,2.
- Gives 1,5-dicarbonyl compounds.
- With an aldol ring closure afterwards: the Robinson annulation.
- The base is regenerated: it is catalytic.
Drawn with 57 atoms, 9 arrows, 8 shapes – every one editable in MolDraw.
Sources
How to use this template
- Press Edit in MolDraw. The template opens on the canvas of the free MolDraw editor.
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Frequently asked questions
Is the Michael addition template free?
Yes. The Michael addition template is one of the free MolDraw templates: open it in the editor or download it from this page as SVG or PNG and use it in your slides, worksheets and notes.
Can I edit the Michael addition template?
Yes. It opens as an ordinary MolDraw drawing, so every structure, arrow, label and colour can be changed, and you can add your own content around it.
Is the chemistry checked?
Every structure is checked with RDKit and every curly arrow passes MolDraw’s electron-flow audit. The sources used are listed on this page.
Which name reactions are included?
Over seventy, covering the reactions most often asked in school-leaving exams (A-level, IB, CBSE, JEE and NEET) and first-year university courses, including condensations, rearrangements, oxidations, reductions and aromatic substitutions.