--- title: "Pentose phosphate pathway: non-oxidative phase Template | MolDraw" url: https://www.moldraw.com/templates/biopath-ppp-nonoxidative/ description: "Pentose phosphate pathway: non-oxidative phase template: Ribulose 5-phosphate → xylulose 5-phosphate (epimerase) and ribose 5-phosphate (isomerase)…" lang: en publisher: Scidart Academy generated: 2026-11-13 --- [MolDraw](https://www.moldraw.com/) › [Templates](https://www.moldraw.com/templates/) › [Biochemistry](https://www.moldraw.com/templates/biochemistry/) › Pentose phosphate pathway: non-oxidative phase [Biochemistry](https://www.moldraw.com/templates/biochemistry/)Premium # Pentose phosphate pathway: non-oxidative phase template ![Pentose phosphate pathway: non-oxidative phase template: Ribulose 5-phosphate → xylulose 5-phosphate (epimerase) and ribose 5-phosphate (isomerase); transketolase (TPP, C₂ transfer) and transaldolase (C₃ transfer) give sedoheptulose 7-phosphate, erythrose 4-phosphate, fructose 6-phosphate and glyceraldehyde 3-phosphate. Open-chain structures with stereocentres.](https://www.moldraw.com/templates/biopath-ppp-nonoxidative.webp) [Edit in MolDraw](https://www.moldraw.com/)Download with Pro Premium template. Preview and edit it free in MolDraw; downloading and exporting it is part of [MolDraw Pro](https://www.moldraw.com/pricing). Ribulose 5-phosphate → xylulose 5-phosphate (epimerase) and ribose 5-phosphate (isomerase); transketolase (TPP, C₂ transfer) and transaldolase (C₃ transfer) give sedoheptulose 7-phosphate, erythrose 4-phosphate, fructose 6-phosphate and glyceraldehyde 3-phosphate. Open-chain structures with stereocentres. ## What the template shows - Epimerase, isomerase, transketolase and transaldolase reshuffle sugar carbons: 3 pentose phosphates → 2 fructose 6-phosphate + 1 glyceraldehyde 3-phosphate - Ribulose 5-phosphate (from the oxidative phase) makes both partners - xylulose 5-phosphate - ribulose 5-phosphate - ribose 5-phosphate - Transketolase (TPP): C₂ unit from a ketose to an aldose - C1–C2 of xylulose 5-phosphate move onto C1 of ribose 5-phosphate - Transaldolase: C₃ unit (dihydroxyacetone) from sedoheptulose 7-phosphate - A lysine Schiff base carries C1–C3 onto glyceraldehyde 3-phosphate - Transketolase again, on erythrose 4-phosphate - Net: 3 ribulose 5-phosphate (3 C₅) → 2 fructose 6-phosphate + glyceraldehyde 3-phosphate (2 C₆ + C₃), back into glycolysis or gluconeogenesis. - Transketolase moves C₂ with TPP (thiamine); its activity in red cells tests for thiamine deficiency (Wernicke–Korsakoff). Transaldolase moves C₃ through a lysine Schiff base. - All steps are reversible: a cell that needs ribose 5-phosphate more than NADPH runs them backwards from fructose 6-phosphate and glyceraldehyde 3-phosphate. - Ketose donors (xylulose 5-P, sedoheptulose 7-P, fructose 6-P) share the D-threo (3S,4R) configuration at C3–C4. Phosphates are drawn un-ionised. Drawn with 206 atoms, 5 arrows, 4 shapes – every one editable in MolDraw. ## Sources - [Nelson & Cox, Lehninger Principles of Biochemistry, 8th ed., 2021, ch. 14](https://openlibrary.org/isbn/9781319228002) Textbook - [Berg, Tymoczko, Gatto & Stryer, Biochemistry, 9th ed., 2019](https://openlibrary.org/isbn/9781319114657) Textbook - [Voet & Voet, Biochemistry, 4th ed., Wiley 2011](https://openlibrary.org/isbn/9780470570951) Textbook - [Racker, de la Haba & Leder, Arch. Biochem. Biophys. 1954, 48, 238](https://doi.org/10.1016/0003-9861(54)90331-8) Original paper - [Horecker & Smyrniotis, J. Biol. Chem. 1955, 212, 811](https://pubmed.ncbi.nlm.nih.gov/14353883/) Original paper ## How to use this template 1. Press **Edit in MolDraw**. The template opens on the canvas of the free MolDraw editor. 2. Change anything: move structures, edit atoms and labels, recolour highlights or delete what you do not need. 3. Add your own structures, arrows and text next to it, or combine several templates on one page. 4. Export the drawing as PNG, SVG or PDF for slides, worksheets, theses and papers. ## Frequently asked questions ### Is the Pentose phosphate pathway: non-oxidative phase template free? You can preview the Pentose phosphate pathway: non-oxidative phase template here and open and edit it in MolDraw for free. Downloading or exporting it is part of MolDraw Pro, together with the other premium templates. ### Can I edit the Pentose phosphate pathway: non-oxidative phase template? Yes. It opens as an ordinary MolDraw drawing, so every structure, arrow, label and colour can be changed, and you can add your own content around it. ### Is the chemistry checked? Every structure is checked with RDKit and every curly arrow passes MolDraw’s electron-flow audit. The sources used are listed on this page. ### Are the biochemical pathways drawn with structures? Yes. Pathway templates show the intermediates as structures, with enzymes and cofactors (NAD⁺, FAD, ATP) on the arrows. ## More biochemistry templates [**Urea cycle**Free · Biochemistry](https://www.moldraw.com/templates/biopath-urea-cycle/)[**Fatty acid β-oxidation**Free · Biochemistry](https://www.moldraw.com/templates/biopath-beta-oxidation/)[**Electron transport chain and ATP synthase**Free · Biochemistry](https://www.moldraw.com/templates/biopath-electron-transport/)[**Light reactions of photosynthesis**Premium · Biochemistry](https://www.moldraw.com/templates/biopath-light-reactions/)[**Calvin cycle**Premium · Biochemistry](https://www.moldraw.com/templates/biopath-calvin-cycle/)[**Pentose phosphate pathway**Premium · Biochemistry](https://www.moldraw.com/templates/biopath-pentose-phosphate/)[**Peptide bond formation**Premium · Biochemistry](https://www.moldraw.com/templates/biopath-peptide-bond/)[**Polymerase chain reaction (PCR)**Premium · Biochemistry](https://www.moldraw.com/templates/biopath-pcr/) ## Related pages [**All Biochemistry templates**56 templates](https://www.moldraw.com/templates/biochemistry/)[**All chemistry templates**458 templates in 31 categories](https://www.moldraw.com/templates/) MolDraw Pro Download all 458 templates - Export the 372 premium templates as PNG, SVG or PDF - AI chemistry assistant - Structure scanning from images - Cloud save and teaching slides [See Pro plans](https://www.moldraw.com/pricing) Free templates stay free. Every template can be opened and edited in MolDraw.